MOTIVATION LETTER Nigeria's pharmaceutical sector faces a documented ratio of one pharmacist per 8,000 people, with rural coverage far worse. Telepharmacy is frequently proposed as the solution, but the literature on Nigerian telepharmacy consists of opinion pieces, pilot reports with N under 50, and policy documents that cite no primary data on infrastructure readiness. I am a licensed pharmacist registered with the Pharmacists Council of Nigeria and a computational researcher who has already conducted one systematic screen of 1,847 records for the CCT model in addiction neuroscience. I propose to write a narrative review for Frontiers in Public Health that applies a structured, reproducible methodology to assess telepharmacy readiness in Nigeria using publicly available data on internet penetration, mobile device access, regulatory frameworks, and pharmacy distribution by state. My dual background makes this feasible. As a clinical pharmacist at Ramset Pharmacy in early 2026, I dispensed medications and managed patient consultations in a setting where telepharmacy could have reduced wait times and improved adherence tracking. As a computational researcher, I have built four independent DuckDB-based ingest-to-analyze pipelines across life-sciences and social-science domains, and I calibrated a 14-parameter Bayesian model using PyMC with priors drawn from a systematic screen. The same skills in evidence synthesis, data extraction, and quantitative reasoning apply directly to this review. My current enrollment in the M.Sc. Digital Health programme at Hasso Plattner Institute and the University of Potsdam adds formal training in digital health evaluation frameworks starting winter semester 2026. The review will follow the SANRA guidelines for narrative reviews. I will define a search strategy across PubMed, Scopus, and African Journals Online with explicit inclusion and exclusion criteria. The thematic analysis will cover four domains: infrastructure (internet penetration, electricity reliability, device access), regulation (PCN telepharmacy guidelines, data protection law), workforce (pharmacist density, digital literacy), and evidence (published pilot studies, their sample sizes, and outcome measures). The discussion will produce a readiness score per domain and identify the three highest-priority gaps for future research. This review is a data-grounded assessment that stakeholders including the PCN, the Federal Ministry of Health, and international funders can use to allocate resources. I am an independent researcher with no institutional backing for this work. That is a limitation I acknowledge and a reason I am applying. The review requires no laboratory access, no ethics approval, and no travel. It requires systematic reading, structured data extraction, and clear writing. I have done all three at scale. SHORT ESSAY: METHODOLOGY The review will follow a pre-registered protocol on OSF before data extraction begins. The search strategy will target PubMed, Scopus, and African Journals Online using a Boolean string combining telepharmacy, telehealth, pharmaceutical care, and Nigeria with country-specific terms for each of the 36 states and the FCT. No date restriction will be applied. Inclusion criteria: English-language publications, any study design, addressing telepharmacy or digital pharmaceutical services in Nigeria. Exclusion criteria: editorials without data, duplicate publications, studies conducted outside Nigeria. Two-stage screening will proceed: title and abstract screening by a single reviewer (myself) with a 10% random sample independently screened by a second reviewer recruited through the Nigerian Association of Pharmacists in Academia. Disagreements will be resolved by discussion. Data extraction will capture study design, sample size, location, technology platform, outcome measures, and reported barriers. Thematic analysis will use a deductive framework based on the four domains described in the motivation letter, with inductive refinement during extraction. Quality assessment will use the Mixed Methods Appraisal Tool for empirical studies and a bespoke checklist for policy documents. A PRISMA flow diagram will document the screening process. The protocol, extraction form, and raw data will be published on Zenodo. SHORT ESSAY: PRACTICAL IMPLICATIONS The review will produce three concrete outputs. First, a readiness matrix mapping each of Nigeria's six geopolitical zones against the four domains, identifying zones where infrastructure is sufficient for a pilot telepharmacy programme and zones where investment in basic connectivity must precede any digital intervention. Second, a prioritized list of regulatory gaps, such as the absence of cross-state licensure for telepharmacy and the lack of data privacy guidelines specific to pharmaceutical consultations. Third, a minimum viable dataset specification for future telepharmacy pilots, defining the variables that must be reported for results to be comparable across studies. These outputs are designed for direct use by the Pharmacists Council of Nigeria in updating its telepharmacy guidelines, by state ministries of health in planning pilot programmes, and by researchers designing the next generation of studies. The review will also identify the three most promising low-cost interventions, such as SMS-based adherence support for chronic disease patients in areas without smartphone penetration, that can be implemented immediately without new legislation. CHECKLIST - [ ] Manuscript formatted to Frontiers in Public Health author guidelines, including abstract, keywords, and references in Vancouver style - [ ] Cover letter addressed to the editor, specifying the article type as Narrative Review - [ ] OSF pre-registration DOI for the review protocol - [ ] ORCID iD (0009-0001-9272-6735) included in manuscript metadata - [ ] Conflict of interest statement: none declared - [ ] Data availability statement: all extracted data will be deposited on Zenodo - [ ] Author contributions statement: sole author - [ ] Figures and tables: readiness matrix (Figure 1), PRISMA flow diagram (Figure 2), priority gaps table (Table 1) - [ ] Supplementary materials: search strategy, extraction form, quality assessment results EDITOR NOTES - Eligibility risk: Frontiers in Public Health does not charge an article processing charge for authors from low-income countries, and Nigeria is on their waiver list. Confirm current waiver policy before submission to avoid unexpected fees. - Verification needed: the 10% independent screening requires a second reviewer. The applicant must identify and confirm a collaborator from the Nigerian Association of Pharmacists in Academia before submission. The profile does not name a specific person for this role. - Gap: the applicant's enrollment at HPI/Potsdam begins winter semester 2026/27. If the review is submitted before that date, the affiliation line should read "Independent researcher, Lagos, Nigeria" not the HPI affiliation. Clarify timeline. - Gap: the applicant's current employment as National Product Manager at Synthcare may create a perceived conflict of interest if Synthcare markets telepharmacy products. Disclose this in the conflict of interest statement and address it briefly in the cover letter. - Fact check: the pharmacist-to-population ratio of 1:8,000 is a commonly cited figure from the PCN but should be verified against the most recent PCN annual report before inclusion in the manuscript.